Grain of kidney of Du Can beneficial fights fatigue drug effect to learn to study Pharmacodynamic Study On The Antifatigue Property Of Dushen Yishen Keli
Purpose experiment observes grain of kidney of Du Can beneficial fights tired out pharmacodynamics action. The method swims again in small rat ligature model, often press next small rat model of oxidation of bandicoot of Wistar of anoxic model, the aged and the small rat kidney that cause by hydroxyl Niao on model of deficiency of yang, observed grain of kidney of Du Can beneficial fights tired out pharmacodynamics action respectively. Result test result makes clear, grain of kidney of Du Can beneficial can lengthen small rat ligature weigh natant time significantly, large dose group (the average ligature of 10g · Kg-1) weighs natant time is NS contrasts the 2 times; of the group is in often approach sodium lime bottle inside, can raise small rat anoxic endurance, large dose can extend small rat surviving time apparently (P ＜ 0.01) , lengthen surviving rate to be able to add the content of the SOD inside red blood cell of bandicoot of the aged Wistar apparently for 82.5 ﹪ ; , SOD is added rate for 75.6 ﹪ , showed stronger fight oxidation (P ＜ 0.01); is in experiment of deficiency of yang of small rat kidney, the effect of deficiency of yang of small rat kidney that can effective antagonism causes by hydroxyl Niao, the weight of spermary and deputy sexual organs increases apparently, raise the content of small rat of kidney deficiency of yang and ketone of spermary of normal bandicoot serum significantly. Grain of kidney of Du Can beneficial has verdict fight exhaustion, be able to bear or endure anoxic, fight action of the oxidation, deficiency of yang that fight kidney, be a kind fight preparation of compound of new drug of tired out Chinese traditional medicine effectively.