Yellow, earthworm is hemp square the most commonly used medicine is opposite remedial asthma one of, the asthma that applies to way of spirit of phlegmy chaotic block is ill. The active ingredient making the same score asthma with yellow hemp basically is hemp Huang Jian (EPH) and bogus hemp Huang Jian (PEPH) .
Yellow, earthworm is hemp square the most commonly used medicine is opposite remedial asthma one of, the asthma that applies to way of spirit of phlegmy chaotic block is ill. The active ingredient making the same score asthma with yellow hemp basically is hemp Huang Jian (EPH) and bogus hemp Huang Jian (PEPH) .
Purpose: The matrix outside teaching straight brown bear to allow the は of Si of ∏ of loose triangular bream of fleeing Zan divide evenly to go to?HMC) hyperplasia and cell (the inhibition of ECM) different composition. Method: ? of border of of Piao of of τ Meng Fu undertakes person HMC is fostered, adopt serum pharmacological method, serum of content of bolus of decoct of preparation turtle shell, use fat polysaccharide (LPS) is exciting factor, application 4 methylic occasionally azotic Zun is blue (the proliferous circumstance that MTT) law detects is velar cell each groups, use adsorption of enzymatic couplet immunity to experiment (ELISA) law detects ECM middle-level is sticky even albumen (LN) and Ⅳ collagen (Col- Ⅳ ) content. Result: LHyperplasia of the MC after PS is exciting and the exudation of the LN in the matrix that fasten film and Col- Ⅳ grow in quantity, have apparent difference quite with blank group (P ＜ 0.01) . Bolus of turtle shell decoct can restrain hyperplasia of the MC below normal condition and LPS exciting condition, have inhibition to the expression of Ⅳ of the LN in ECM, Col- . Conclusion: Ash of Wan of accurate fleeing tenon plants brown bear the expression that the は of Pu goes to? of head crucian carp to restrain kidney spherule is the LN in velar matrix and Col- Ⅳ , reduce the accumulation of ECM, this may be disease of spherule of kidney of its prevention and cure, defer the partial action mechanism of kidney spherule sclerosis.
The expression that the purpose discusses 2(AQP2) of albumen of nephritic water passageway and metabolization of fluid of water of diabetic nephrosis bandicoot are unusual reach lustre the mechanism of action of prevention and cure of yellow decoct agent. The method adds small dose STZ with stimulation of feed of tall fat of high in syrup model of duplicate diabetic bandicoot, random cent contrasts for model group, positive group, lustre yellow decoct group, set normal group additionally. Immune systematism learns to detect AQP2 is in kidney of each groups of bandicoot distributings mediumly the expressive;RT-PCR method that reachs protein detects the expression of AQP2mRNA of each groups of bandicoot, and with β - Actin is relatively mensurable. Group of result lustre yellow decoct and positive contrast albumen of make water of group of hollow blood sugar, 24 h is excreted rate relatively model group all drops significantly. Kidney immunity group is changed show: AQP2 basically provides expression in nephritic gather. Compare with model group, lustre the expression of the nephritic AQP2 albumen of animal of yellow decoct group, AQP2mRNA all is reduced apparently (P ＜ 0.05) . The AQP2 in organization of kidney of bandicoot of conclusion model group conveys grow in quantity, AQP2 grow in quantity may participate in the formation of diabetic much make water. Lustre yellow decoct agent to water passageway albumen the expression of 2 has reduce effect, this may be its adjust the mechanism of action of water fluid metabolization, also be its prevent the foundation that treats diabetic nephrosis.
Powered by WordPress