Herbal Medicine

Purpose: Core of feel ashamed of Qiu of Zou of ü  Jin is engraved religion treat Gan to go to  Wan to mound?M.S of kind of Guo of Ω department  is vaccinal) crowd security and be able to bear or endure suffer a gender, preliminary observation skin of crowd of tall to tuberculosis danger tries this vaccine the influence of reaction intensity. Method: Inject of volunteer of?5 exemple health is different the vaccine of dosage (8.7, 17.5 with 35.0 μ G) , every inject 6 times, every 2 weeks inject 1 times. Suffer the person that try through be opposite along with visit, X- of convention of fluid of convention of heartbeat and blood pressure test, blood, make water, liver function, bosom piece and the B of liver, bravery, lienal, pancreas exceeds experiment of examination and PPD skin, evaluate the harmful response of M.S vaccine, compare the change of intensity of reaction of PPD of vaccinal inject around. Result: In process of injection of vaccine of 330?5 exemple, second M.S, produce 14, 17 second spend harmful response gently, include local ache, lymph node enlargement, calorific, local scleroma, flustered, rash and lack of power, spend harmful response total occurence rate gently to be 25.5 ﹪ (14/55) , in happening, spend reach classics of the person that spend skin of harmful response;PPD to try strong positive again the inject of vaccine of different dosage M.S, PPD skin tries reaction intensity to all be reduced significantly (P ＜ 0.05) . Conclusion: M.S vaccine has higher security, can reduce skin of PPD of crowd of tuberculosis tall danger to try the intensity of reaction significantly.

The expression that the purpose discusses 2(AQP2) of albumen of nephritic water passageway and metabolization of fluid of water of diabetic nephrosis bandicoot are unusual reach lustre the mechanism of action of prevention and cure of yellow decoct agent. The method adds small dose STZ with stimulation of feed of tall fat of high in syrup model of duplicate diabetic bandicoot, random cent contrasts for model group, positive group, lustre yellow decoct group, set normal group additionally. Immune systematism learns to detect AQP2 is in kidney of each groups of bandicoot distributings mediumly the expressive;RT-PCR method that reachs protein detects the expression of AQP2mRNA of each groups of bandicoot, and with β - Actin is relatively mensurable. Group of result lustre yellow decoct and positive contrast albumen of make water of group of hollow blood sugar, 24 h is excreted rate relatively model group all drops significantly. Kidney immunity group is changed show: AQP2 basically provides expression in nephritic gather. Compare with model group, lustre the expression of the nephritic AQP2 albumen of animal of yellow decoct group, AQP2mRNA all is reduced apparently (P ＜ 0.05) . The AQP2 in organization of kidney of bandicoot of conclusion model group conveys grow in quantity, AQP2 grow in quantity may participate in the formation of diabetic much make water. Lustre yellow decoct agent to water passageway albumen the expression of 2 has reduce effect, this may be its adjust the mechanism of action of water fluid metabolization, also be its prevent the foundation that treats diabetic nephrosis.