New drug considers to develop cost and Analysis Of The Cost And Influence Factors Of New Drug R
The new drug that the whole world appeared on the market 2006 35, among them 21 are the new chemical object that appears on the market first (New Chemical entities, NCEs) , have those who use success of biology technology research and development additionally all sorts of vaccine and recombine albumen kind new drug in all 14. Press curative effect classification, appear on the market most is to fight infection medicaments 10 (occupy 28.58 ﹪ ) , fight tumor medicaments 7 (occupy 20 ﹪ ) , digestion uses medicine and eye disease to use drug with medicine, blood disease with medicine, cardiovascular system each 2 (each occupy 5.71 ﹪ ) , other remedy 10 (occupy 28.58 ﹪ ) . Specific content detailed sees a table 1.
Fight as a kind coagulate medicine of the fine that prevent bolt, bloodsucker element (the research that Hirudin) recombines bloodsucker element especially is increasingly thorough. Put a few limitation that be in in the light of bloodsucker element, the haemorrhage risk with still exist if half-life is short, clinical particular when application, effect that prevents arterial thrombus is not ideal wait, a few new bloodsucker element derivative, recombine peptide of bloodsucker element imitate to be in research and development, be opposite at the same time the different approach giving drug of bloodsucker element / the research of means and new the form of a drug also is begun in development. The drug that combines bloodsucker element now is moved learn / the research that medical effect learns the respect such as action of feature, pharmacodynamics is right bloodsucker element (include to recombine bloodsucker element) different approach giving drug, be not inject to if ministry of profess to convinced, lung, nasal cavity, eye gives medicine to wait,give medicine the way especially, and relevant the form of a drug if inject of macromolecule union other people gives medicine delay commentate system, carapace gets together candy - tiny ball of bolus of Shi Wei of agent of small bag of alga acerbity salt or PEG- alga acerbity salt, rhinal sparge, delay, PLGA the research that wait makes progress undertake summing up, with period the farther clinical application that is bloodsucker element provides scientific basis.
Tumour of flesh and blood is to send the malignant tumor at bone formerly, much hair reachs children at adolescent, occupy the 5 ﹪ of children tumour about. Because cure is changed after art, especially new assist the application that turns cure, already made 5 years of survival rate of patient of tumour of flesh and blood raise 60 ﹪ ~ inside 20 years in the past 70 ﹪ . In recent years as new auxiliary those who change cure is extensive begin, its are protected limb is led and generate rate all have rise apparently, but clinical go up to be able to bear or endure to much medicine medical case is added gradually much [1] . The classics proved recipe that solving drug Yu just is tumour of flesh and blood of this academy cure, clinical application can alleviate effectively aching, reduce local strut, raise patient life quality and survival rate. The author observed the ossification caruncle cell that fosters outside body is U2-OS its are right grow influence.
“Medicine person poison also ” , “The face ” that medicaments is like a knife, this is the dangerous sex that in urge medicines and chemical reagents use place has. Basis ” standard of quality of product of People’s Republic of China ” the 15th the 5th regulation, use undeserved, create the product that product itself damages or endangers security of person, belongings possibly easily, ought to have caution indicates or Chinese caution explains.
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