Herbal Medicine

Tumor patient often appears in the process that change cure disgusting vomiting, appetite drops, listless and lack of power, leucocyte issues demote poison deputy response, make a constitution feeble, life quality drops, serious when can appear amalgamative disease endangers life even. ～ applied the author to join inject fluid painstakingly to reduce lung cancer to change the intention of the poisonous deputy reaction of cure patient in December 2005 in October 2003, report as follows now.

Purpose: PLC of 蜨 of  ⒑ Hu digitlizes dactylogram a collection of illustrative plates, for red ginseng quality control provides a basis. Method: Law of PLC of 郒 of  Mei Cong analyses red ginseng 75 ﹪ (V/V) alcohol extracts content, use post of Century SIL C18 AQ (25cm X4.6 Mm, 5 μ M) , photograph of going from place to place is 0.1 Mol/L NaH2PO4 aqueous solution - second nitrile, linear gradient wash out, detect wavelengh 203 nm, column is lukewarm (℃ of 30 ± 0.15) , measure 20 μ L into appearance. With F of index of a collection of illustrative plates of color atlas dactylogram, qualitative likeness spends SF and mensurable likeness to spend the digitlization index such as P ﹪ to undertake evaluating. Result:  of Li of Zhan of charm a surname grasps miasma to carve? shares a peak 30 times certainly, announced adequately of a collection of illustrative plates of dactylogram of red ginseng HPLC exceed news feature. Conclusion:   ⒌ is troubled by liver fall forward? of Yun of sell of ㄊ of ⒆ of bath of an ancient small-mouthed wine vessel of plan vertebra grandma having enough has very good precision and repeatability, comfortable Yu Gong joins quality to control.

The purpose discusses a kind new ginseng is rare black glucoside 20-O-(β - dextrose of D- Bi Nan) - 20(S)- protoplast joins glucoside of 2 mellow black (IH-901) is right the hyperplasia of cell of BEL-7402 of person liver cancer restrains the effect and revulsive wither to die action. Method with 0, 6.25, 12.5, 25, 50, 75, the IH-901 action of 100 μ Mol/L the BEL-7402 cell at the education outside body, detect through MTT law the inhibition that IH-901 grows to the cell, differ configuration of microscope observation cell changes, the fluorescent nucleus coloring of AO/EB observes wither dies cellular configuration, art of cell drifting type detects cellular cycle and cellular wither die. Result MTT experiment shows IH-901 restrains the growth of BEL-7402 cell, observe typical wither dies below the means; microscope that shows time and chroma to depend on configuration change and biochemical feature: Go to  to wade agglomeration of? nucleus chromatin, occurrence wither dies after the fluorescent nucleus coloring of small system;AO/EB, observe typical wither dies cellular; sheds type cell appearance to be able to detect to wither die peak, and the cell is in by block sluggish G0/G1 period. The means that conclusion IH-901 can die through revulsive cell wither restrains the growth of cell of BEL-7402 of person liver cancer effectively, IH-901 of glucoside of rare ginseng black may become a kind to fight medicaments of cancer of the liver potentially.

Suffering joins alkaline crystallization, document reports the method that uses oil aether normally. The fruit of foreign matter pagoda tree that joins alkaline middling painstakingly to contain chemical structure likeness is alkaline, pure the method that crystallizes with oil aether, cannot fruit of eliminate pagoda tree is alkaline. Suffering joins method of alkaline underwater crystallization, at present home has not appear in the newspaper, we use bitter ginseng alkaline crystal in water, fruit of detached pagoda tree is alkaline, combine the recrystallization of oil aether, remove rarefied suffering to enter alkaline intent.

Bitter ginseng belongs to a plant to be joined painstakingly for leguminous pagoda tree (the dry root of Sophoraflavescens Ait) , have clear hot dry wet, kill function of bug, diuresis [1] . The active part in be being joined painstakingly basically is alkaloid and yellow ketone two kinds big, on annulus of A of bitter ginseng yellow ketone discrepant Xi of the fifth of the ten Heavenly Stem is replaced base existence, and most yellow ketone is in the C8 of A annulus on replace base with the ramose different the fifth of the ten Heavenly Stem of Lavandulyl form of catenary of Xi radical side exists, xi radical changes the different the fifth of the ten Heavenly Stem of yellow ketone the close fat sex that increased yellow ketone compound, make its pass through cellular film more easily inside organism to reach action goal, consequently Xi of different the fifth of the ten Heavenly Stem base yellow ketone is had stronger fight microbial active, fight the phlogistic active, active that fight cancer and cheese ammonia acid enzymatic restrain active [2] . The research of the chemical composition that joins yellow ketone compound domestic and internationally to suffering at present and pharmacodynamics action is very active, but the article that analyses about joining yellow ketone content painstakingly did not appear in the newspaper. This literary grace determined with ultraviolet and prismatic photometry ketone content always fizzles out in bitter ginseng, discover this way fast, accurate, error is small.

Purpose: The root of Chinese trichosanthes of? of handkerchief of earnest of blood clam of quiet of ㄌ of error of generation of  ⑼  , yam, red ginseng, rhizome of wind-weed, the root of remembranous milk vetch) the method of content of Rb1 of glucoside of black of Re of glucoside of black of Rg1 of glucoside of go-between ginseng black, ginseng, ginseng. Method: The content that law of PLC of 肏 of take along sth to sb realizes Rb1 of glucoside of black of Re of glucoside of black of Rg1 of pair of ginseng black glucoside, ginseng, ginseng determines, it is analytic column with chromatographic column of M) of μ of 250 Mm;5 of Diamonsil C18(4.6 Mm × , with second nitrile - 0.05 ﹪ phosphoric acid detects for; of photograph of going from place to place wavelengh is 203 nm. Result: There is better depart to spend between Re of glucoside of black of Rg1 of glucoside of black of ginseng of? of  of Qiong of grow of Yi old  , ginseng and Rb1 of ginseng black glucoside, there is good linear concern between the chroma of 3 kinds of composition and respective peak area, precision, stability, reappearance and add appearance to reclaim the relative standard deviation of rate all is less than 3 ﹪ . Conclusion:  of Jing any of several hot spice plants admires blood clam of quiet of ㄌ of  generation error to sincere graceful twinkling of handkerchief V instrument lies Re of glucoside of black of Bian 誖 G1, ginseng and Rb1 of ginseng black glucoside, the quality that can regard sugar make water as happy grain controls a medium.

The agent that bolus of easy bosom drop is ” of sternum of easy of Chinese pharmacopoeia ” changes breed [1] , by 37, composition of safflower, the rhizome of chuanxiong, have Yu of invigorate the circulation of blood, dispel, acetanilide effect, curative effect is exact. But, easy sternum is existing dissolve goes out slow, have effect availability of slow, biology is low, take drug to measure big, patient to comply with a gender low defect.

Purpose: Huang of ⑸ of  of revive of Wei of accuse falsely teaching plant dries up Yi eggplant picks up instrument of ┓ handkerchief riverside to seek; Method of ぷ Yong? : Random cent is patient of cancer of?8 exemple nose pharynx two groups, remedial group (put cure ginseng Qi is helped up injecting fluid) mix 30 times contrast group (pure put cure) 28. The weight to two groups of patients, Karnofsky gives a mark and change of reaction of oral cavity mucous membrane, leucocyte undertakes observing contrast. Result: Piao ψ pure?Karnofsky gives a mark) remedial group and contrast of the group raise stable rate to be mixed for 90 ﹪ respectively 60.7 ﹪ , p ＜ 0.05; treats rate of group of gain weight stability to be 93.3 ﹪ , contrast group for 67.9 ﹪ , stomatitis of radioactivity of P ＜ 0.05; contrasts groups of group of apparent overweight treatment, white blood cell of blood of the week outside P ＜ 0.05; drops contrast group relatively remedial group is apparent, p ＜ 0.05. Conclusion: Eggplant of ticket of acute communicable diseases of riverside of handkerchief of play of creek of date of Huang of ⑸ of  of revive of accuse falsely Wei picks up ┑ act buccal? to be able to improve life quality of the patient, reduce harmful response of the patient.

Rg1(Ginsenoside Rg1 of glucoside of black of purpose research ginseng, rg1) is methylic to 1- 4- phenyl - 1, 2, 3, 4 hydrogen of 6- pyridine (1-methy-4-phenyl-1, 2, 3, 6-tetrahydropyridine, MPTP) causes Pajinsen disease small rat is black qualitative (Substantia nigra, SN) is much cling to amine (Dopamine, DA) can nerve yuan metamorphic protective action and its are likely mechanism. Small rat divides methodological C57BL6 randomly to contrast group (NS, group of Ip) , MPTP (5d of × of 30mg · Kg-1, ip) reachs 8d of × of Rg1(5mg · Kg-1, ip) pretreatment group. Applied changeover is recorded - aggregate enzymatic chain reaction (the technology such as chemical coloring of organization of RT-PCR) , immunity observed hydroxide of acid of ammonia of SN Caspase-3 MRNA, Bcl-2 MRNA, Bax MRNA, cheese is changed enzymatic (Tyrosine hydroxylase, the expressive level of TH)mRNA and black qualitative compact band (Substantia Nigra Zona compacta, the change of the multinomial index such as amount of cell of positive of SNzc)TH immunity reaction, detect with law of color atlas of concentrated juice photograph system of state of small rat grain (Striatum, the DA inside Str) and its metabolization content second of 2 hydroxyl benzene is acerbity (Dihydroxyphenylacetic acid, DOPAC) and tall sweet oxalic acid (Homovanillic Acid, HVA) content. The content of the DA inside amount of electropositive cell of the TH inside SN of result MPTP group, Str and DOPAC of its metabolization child and HVA decreases apparently, after applying Rgl but changeover afore-mentioned changes (the expression of SN Bcl-2, TH MRNA reduces troop of P ＜ 0.01).MPTP apparently (the expression of P ＜ 0.01);Caspase-3, Bax mRNA increases apparently (P ＜ 0.01) . After applying Rg1 reversible turn afore-mentioned changes (P ＜ 0.05) . Conclusion Rg1 sends SN DA of small rat of Pajinsen disease to MPTP can nerve yuan have apparent protective effect, its mechanism likelihood and fight wither to die the process is concerned.