Herbal Medicine

Diabetic it is current whole world main clinical with communal and healthy problem, especially 2 model diabetic occupy diabetic 80 ﹪ above. Thinking insulin resistance and cell of pancreas islet β secrete blemish at present is 2 model 2 when diabetic hair interpretation of the cause makes main link. In recent years, as right 2 model the thorough research that diabetic hair interpretation of the cause makes, discovered many medicationed new target are nodded, synthesized a series of new active compound. Show near a few years 2 model diabetic cure new drone reachs his the research of new guide compound undertakes inducing summing up, provide certain reference for new drug research and development.

The purpose understands 2 model after the diabetic leaves hospital current situation of sex of comprehensive treatment comply with, discuss influencing factor, make corresponding countermeasure. The method uses questionnaire form to investigate 65 in September 2005 ～ in April 2006 ever of hospitalization 2 model diabetic, after evaluating its to leave hospital, medication, dietary cure, motion treatment, ego is monitored, check regularly the comply with circumstance that waits for a respect. The comply with sex that treats behavior each according to giving a mark as a result from it is high to low ordinal sort medication, dietary cure, motion treatment, fixed check, ego monitors; and general and objective element is opposite 2 model the comply with sex that the diabetic treats integratedly does not have distinct effect it seems that (all. Conclusion diabetic already accepted diabetic comprehensive treatment gradually, but the sex of remedial comply with that be monitored to ego and checks regularly still remains to rise further.

Purpose application medicine is moved learn to learn to combine a model with medical effect, watch of the bases in total alkaloid of research board blue root is accused according to spring the medicine inside body of the yeasty bandicoot that send heat is moved learn to learn the relation between with medical effect. The method gives bandicoot total alkaloid of Ig board blue root, different time takes blood and have observation to temperature, use doctrine of concentrated juice look to determine the watch in plasma is accused according to spring chroma, with model of one room room computational medicine is moved learn parameter, use 3 kinds of medicine to move learn to learn to plan to combine a model with medical effect, learn parameter to undertake planning to close to medical effect respectively. As a result the watch is accused according to spring the main medicine inside normal bandicoot and calorific bandicoot body is moved learn parameter T1/2, Cmax, AUC to be respectively: (4.94 ± 0.84)h, (G/mL of μ of 4.01 ± 0.21) , (H/mL of · of G of μ of 28.37 ± 2.42) and (5.71 ± 0.91)h, (G/mL of μ of 4.15 ± 0.25) , (H/mL of · of G of μ of 30.35 ± 2.58) . It is better that the relation between pharmacodynamics effect and effect room chroma uses the medical effect generation in indirect reaction to restrain a model to plan to close, corresponding medical effect learns parameter to be for Kin respectively (0.7 ± 0.10)h-1, kout is (0.54 ± 0.12)h-1, r0 is 1.33 ± 0.16, IC50 is (0.94 ± 0.66)mg/L. The watch in total alkaloid of conclusion board blue root is accused according to spring the medicine inside normal bandicoot and calorific bandicoot body is moved learn behavior not to have apparent difference, the watch is accused according to spring inside calorific bandicoot body medicine is moved learn to learn a medical effect generation in according with indirect reaction to restrain a model with medical effect.

Uterine flesh tumour is the benign tumor with female genital most common lawsuit, good hair at Yo age woman. Although flesh tumour itself is much,have a symptom rarely, but wait because of flesh tumour position and denaturation bring about an uterus abnormal haemorrhage, afterwards sends severe anemia, pelvic cavity oppressive symptom and ache, make one of main reasons that uterine flesh tumour makes hysterectomy.

Purpose: Abdomen of Juan soot Nao is proud nucleus of the root of herbaceous peony of heart  ? , the seed of cowherb, tangerine) the influence of the prostate viscera coefficient of prostatitis disease model and pathology histology reachs sex of bacterium of chronic to bandicoot blame its are right the action of general inflammation and aching model. Method: Makeup mew of Lang of a cricket of ┞ hole bed is affectedly sweet be proud Xing? infuse model of prostatitis of preparation of fluid of inject of spirit of naevus of 25 ﹪ disappear, prostate organization is taken to determine after giving drug continuously index and pathology examination. Use the inflammation model with bandicoot tampon swollen granulation and the aching model that heat up board law to observe its are fought phlogistic with demulcent action. Result: The prostate viscera coefficient that Nao abdomen is proud? of  of father of bridle of Lian of bed of source of heart   can reduce bandicoot of model of prostatitis of be caused by of fluid of disappear naevus quick injection, pathology change; that improves model bandicoot prostate reduces; of swollen weight of bandicoot tampon granulation to raise heat board standard small rat is painful. Conclusion: Nao abdomen is proud Yun of  of Fu of a key to do sth of center of  of month of Yue of flute of bed of bed of source of heart   is proud? of Yong of chart of acute communicable diseases of elder brother of smile of Xing Chi clumsy

Purpose: Small cup of lamp of? of counterfeit of Juan Shi Xi is spent) to diabetic nephrosis (DN) cruor / the influence of fine dissolve. Method: DN patient divides?8 exemple to be mixed for remedial group randomly contrast group, on treatment of diabetic nephrosis basics, remedial group is added with Maidetong, contrast group add with fluid of inject of the root of red-rooted salvia of medicine made of two or more ingredients. Treat ration of albumen of around 24 h make water, Ccr, Scr and cruor quite / the change of fine dissolve index. Result: Period of treatment of? of acute communicable diseases (2 weeks) hind, ration of albumen of make water of remedial group 24 h decreases significantly (P ＜ 0.05) , Ccr, Scr is improved significantly (P ＜ 0.05) , contrast group therapy around does not have difference (P ＞ 0.05) , the two across block after cure compare difference remarkable (the VWF:A after P ＜ 0.05); treats group of cureG, Fbg and FPA level all are reduced significantly (P ＜ 0.05) , of D-dimer, PF1 2 and PAI-1 reduce special significance (P ＜ 0.01) , and AT- Ⅲ : A, TPA and PIC level all rise significantly (P ＜ 0.05) , PLG raises special significance (P ＜ 0.01); and contrast the two across block after remedial around all did not see group of each observation index change; to treat significantly are compared, the difference of each index all has significance sense (P ＜ 0.05 or P ＜ 0.01) . Conclusion: Condition of Gao Ning of N of 艱 of accept of lofty of Xi counterfeit  , reduce albuminuria, improve kidney function, to deferring DN development has active sense.

Hamster of purpose research China is ovarian epithelial (Chinese Hamster Ovary Cell, whether does CHO cell) convey albumen kinase C(protein Kinase C, PKC)l inferior model. The method consults GeneBank database PKCl inferior model the CLUSTALW that CDNA alignment; passes EMBL-EBI database, choose kind belong to the alignment; with a highest sex that be the same as a source to use GENERUNNER software to design PKCl, inferior model enlarge of the distinctive;RT-PCR that make thing adds CHO cell PKCl inferior model CDNA alignment; uses AT clone technology to go to PKCl join on PGEM-T carrier, choose via blue blaze, enzymatic foreword;Western blotting method is measured to detect after cutting appraisal the PKCl in CHO cell inferior model. Result RT-PCR and Western blotting technology confirm CHO cell conveys PKCl inferior model, confirm via measuring order. PKCl discovers in conclusion CHO cell inferior model existence, study PKCl for development inferior model structure, function and turn with the signal inside the cell guide the relation of access lays a foundation.