Herbal Medicine

January 3, 2008

Fight diabetic medicaments dimension to amount to Lie Ting Vildagliptin:aNovel Oral Antidiabetic Agent

Filed under: China Drug Magazine — Tags: , , , , , , , — admin @ 5:14 am

Weidalieting is the particularity with a kind of effective profess to convinced 2 peptide base peptide enzymatic Ⅳ (DPP- Ⅳ ) depressor, can enhance peptide of appearance of pancreas tall blood sugar I(GLP-1) active and reduce 2 model the symptom of tall blood sugar of the diabetic. Consider to make clear, no matter Weidalieting is sheet is used or with its he fights diabetic medicaments operable, all can reduce the sugar that has clinical sense apparently base change haemoglobin (HbA1c) level, have be able to bear or endure goodly suffer a gender, and wait for harmful response without gain weight and dropsy, the harmful response occurence rate such as hypoglycemia and gastric bowel path is inferior also. Move to its pharmacodynamics action, medicine now learn, clinical research and harmful response undertake summing up.

December 26, 2007

Ting Li child the influence Effect Of Aqueous Extract From Semen Lepidii Seu Descurainiae On Ventricular Remodeling In Experimental Animals that water carries fluid to reframe to ventricle of animal experiment sex

Filed under: Traditional Herbal Research — Tags: , , , , , , , , — admin @ 8:00 pm

Li of purpose research Ting child water carries fluid to be opposite different third adrenalin (ISO) causes small rat, l- thyroid element (the effect that L-Thy) causes ventricle of bandicoot experiment sex to reframe. Methodological small rat everyday Sc ISO 2 Mg/kg, bandicoot of successive 7 D; everyday Ip L-Thy 0.3 Mg/kg, successive 10 d, preparation ventricle reframes animal model. Each groups of small rat everyday Ig Ting Li child water carries fluid 6, 12 G/kg and beauty hold Luo Er 0.06 G/kg in the palm, after successive 7 d, detect adenosine of phosphoric acid of heart index, serous annulus (blood-vessel of CAMP) , cardiac muscle is nervous element Ⅱ (Ang Ⅱ ) the metabolic; of the quantity each groups of bandicoot everyday Ig Ting Li child water carries fluid 4, 8 g/kg and Katuopuli after 0.02g/kg 10 D, detect ketone of solid of the aldehyde in heart index, plasma (proline of ALD) and Ⅱ of Ang of left cardiac muscle, hydroxide (the change that Hyp) measures. Quantity of Ⅱ of the heart index of result model small rat, CAMP, Ang all lifts apparently, give beautiful Tuoluoer 0.06 g/kg or Ting Li child water carries fluid 12 G/kg to all can restrain small rat Zun Xin room to reframe with fleshy, the amount that reduces heart index and serum CAMP level and Ⅱ of cardiac muscle Ang (P < 0.05) . Model bandicoot also appears cardiac muscle fiber is changed, quantity of Hyp of Ⅱ of Ang of heart index, cardiac muscle, serous ALD, cardiac muscle all lifts apparently, give Katuopuli 0.02 g/kg or Ting Li child water carries fluid 4, 8 G/kg all can reduce bandicoot heart index and Ang Ⅱ , ALD and level of cardiac muscle Hyp (P < 0.05) . Conclusion Ting Li child water carries fluid to have the effect that restrains hypertrophy of experimental animal cardiac muscle, ventricle to reframe, its action mechanism likelihood and control sympathetic system stimulant reach restrain the nerve such as Ang Ⅱ , ALD endocrine factor activation is concerned.

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